Welcome to our Coumarin FAQ (Frequently Asked Questions).
Here we try to answer questions about Coumarin and are principally focused on the
issues relevant to Coumarin skin allergy sufferers.
Please contact us if you have a question or answer about
Coumarin that you would like to see here and certainly if we have got something wrong!
Coumarin is a phytochemical with a vanilla like flavour.
Coumarin is an oxygen heterocycle. Coumarin can occur
either free or combined with the sugar glucose, coumarin glycoside.
Where is Coumarin found?
Coumarin is produced by some plants and is most notably found in Tonka bean, woodruff, lavender,
sweet clover grass, celery and licorice. It is also found in citrus fruits, strawberries, apricots,
cherries, and cinnamon.
What does Coumarin smell like?
It has a sweet scent, readily recognised as the scent of newly-mown lawns (as beloved by
hay-fever sufferers).
What does Coumarin look like?
So you want to stare out your enemy? You'd better squint. This is what it looks like under a
microscope.
What is Coumarin used for?
It's quite versatile is Coumarin.
In its natural state the plants that contain it seem to use it as some sort of pesticide.
Us humans use it for dye, fragrances (it's very big in the cosmetics industry), flavourings and
rodent poison.
Medically it is also popular as it has the following properties:
anti-coagulant (especially
warfarin), blood thinning, anti-fungal, anti-tumour,
antineoplastic.
It is a suspected carcinogenic and is therefore no longer an ingredient in cigarettes.
It's also very good for causing eczema on the human skin (itch, scratch) : (
Imperatorin is a furocoumarin and a
phytochemical
derived from the Malvaceae family of
flowering plants that includes the mallows, cotton plants, okra, hibiscus, and hollyhocks.
Is consumption of Coumarin dangerous?
Despite its flavour enhancing properties, numerous studies, beginning in 1855, have indicated
that coumarin has toxic effects on the nervous system, heart, blood vessels, and liver
of animals as well as inducing cancerous tumours and toxic conditions in humans.
In 1954, the US Food and Drug Administration (FDA) banned coumarin in food, but not
tobacco products, in the USA based on the results of animal research. Also, since 1954, many
European countries have either banned or greatly restricted coumarin because of its
toxic properties. In Norway, like the USA, coumarin has been banned in food, but not in tobacco.
For additional information from Skin Deep see
http://www.ewg.org/reports/skindeep2/report.php?type=INGREDIENT&id=1117.
Does Coumarin have a chemical name or formula?
Yes. Coumarin is known chemically as Alpha Benzopyrone and has the formula
C9H6O2.
It is also sometimes referred to as Cumarin, Benzopyrone or Tonka Bean Camphor.
Anti-Coagulant
An anti-coagulant is a substance that prevents coagulation; that is, it stops blood from clotting.
Antineoplastic
An antineoplastic is a substance that inhibits or prevents the growth of neoplasms, checking the
maturation and proliferation of malignant cells.
Furocoumarin
Some plants contain furocoumarins, which are photoactive compounds. Examples of
furocoumarin-containing fruits and vegetables include limes, lemons, celery and parsley.
Exposure to a furocoumarin-containing substance does not cause a skin eruption in the
absence of exposure to ultraviolet light.
Oxygen Heterocycle
We're not entirely sure what this is but think it's a chemical term for organic one-ring
compounds containing oxygen.
Can you tell us what an oxygen heterocycle is?
Phytochemical
Phytochemicals are non-nutritive plant
chemicals that have protective or disease preventive properties. There are more than a thousand
known phytochemicals. It is well-known that plants produce these chemicals to protect themselves but
recent research demonstrates that many phytochemicals can protect humans against diseases.
Some of the well-known phytochemicals are lycopene in tomatoes, isoflavones in soy and flavanoids
in fruits. Phytochemicals are not essential nutrients and are not required by the human body for
sustaining life.
Warfarin (also known under the brand name Coumadin) is an anticoagulant medication that can be
administered orally. It is used for the prophylaxis of thrombosis and embolism in many disorders.
Its activity has to be monitored by frequent blood testing for the international normalized ratio
(INR).
Warfarin was originally developed as a rat poison, and is still widely used as such, although
warfarin-resistant rats are becoming more common.
Coumarin Links
Coumarin - see what it looks like under a
microscope.